Rastelli, Giulio : rechercher sur Z-Library

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Don't use scam websites

Livres
Articles (97)
Les plus populaires
Liste
- Liste
- Tableau

1

Fast and accurate predictions of binding free energies using MM-PBSA and MM-GBSA

Giulio Rastelli, Alberto Del Rio, Gianluca Degliesposti, Miriam Sgobba

Journal:

Journal of Computational Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 287 KB

english, 2010

2

Relationship between quantum-chemical descriptors of proton dissociation and experimental acidity constants of various hydroxylated coumarins. Identification of the biologically active species for xanthine oxidase inhibition

Anna Maria Ferrari, Miriam Sgobba, Maria Cristina Gamberini, Giulio Rastelli

Journal:

European Journal of Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 170 KB

english, 2007

3

Structure-Based Design of Potent Aromatase Inhibitors by High-Throughput Docking

Caporuscio, Fabiana, Rastelli, Giulio, Imbriano, Carol, Del Rio, Alberto

Journal:

Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 3.56 MB

english, 2011

4

Docking and Database Screening Reveal New Classes of Plasmodium f alciparum Dihydrofolate Reductase Inhibitors

Rastelli, Giulio, Pacchioni, Sara, Sirawaraporn, Worachart, Sirawaraporn, Rachada, Parenti, Marco Daniele, Ferrari, Anna Maria

Journal:

Journal of Medicinal Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 600 KB

english, 2003

5

Oxidative Modification of Aldose Reductase Induced by Copper Ion. Factors and Conditions Affecting the Process †

Cecconi, Ilaria, Moroni, Maria, Vilardo, Pier Giuseppe, Dal Monte, Massimo, Borella, Paola, Rastelli, Giulio, Costantino, Luca, Garland, Donita, Carper, Deborah, Petrash, J. Mark, Del Corso, Antonella

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 78 KB

english, 1998

6

Molecular Dynamics Simulations and Classical Multidimensional Scaling Unveil New Metastable States in the Conformational Landscape of CDK2

Pisani, Pasquale, Caporuscio, Fabiana, Carlino, Luca, Rastelli, Giulio, Soares, Claudio M

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 5.21 MB

english, 2016

7

Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis

Everard, Amandine, Plovier, Hubert, Rastelli, Marialetizia, Van Hul, Matthias, de Wouters d’Oplinter, Alice, Geurts, Lucie, Druart, Céline, Robine, Sylvie, Delzenne, Nathalie M., Muccioli, Giulio G.,

Journal:

Nature Communications

Année:

2019

Langue:

english

Fichier:

PDF, 3.49 MB

english, 2019

8

Refinement and Rescoring of Virtual Screening Results

Rastelli, Giulio, Pinzi, Luca

Journal:

Frontiers in Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 477 KB

english, 2019

9

Diabetes complications and their potential prevention: Aldose reductase inhibition and other approaches

Luca Costantino, Giulio Rastelli, Paola Vianello, Giorgio Cignarella, Daniela Barlocco

Journal:

Medicinal Research Reviews

Année:

1999

Langue:

english

Fichier:

PDF, 236 KB

english, 1999

10

Preparation of Thieno[3,2-h]cinnolinones as Matrix Metalloproteinase Inhibitors

Gérard A. Pinna, Maria M. Curzu, Gabriele Murineddu, Giorgio Chelucci, Giorgio Cignarella, Ernesto Menta, Hans W. Krell, Giulio Rastelli, Anna M. Ferrari

Journal:

Archiv der Pharmazie

Année:

2000

Langue:

english

Fichier:

PDF, 221 KB

english, 2000

11

Synthesis and cytotoxicity of bis(benzo[g]indole-3-carboxamides) and related compounds

Gérard A. Pinna, Maria A. Pirisi, Giuseppe E. Grella, Laura Gherardini, Jean M. Mussinu, Giuseppe Paglietti, Anna M. Ferrari, Giulio Rastelli

Journal:

Archiv der Pharmazie

Année:

2001

Langue:

english

Fichier:

PDF, 91 KB

english, 2001

12

ChemInform Abstract: Diabetes Complications and Their Potential Prevention: Aldose Reductase Inhibition and Other Approaches

Luca Costantino, Giulio Rastelli, Paola Vianello, Giorgio Cignarella, Daniela Barlocco

Journal:

Année:

1999

Fichier:

PDF, 24 KB

1999

13

ChemInform Abstract: Preparation of Thieno[3,2-h]cinnolinones as Matrix Metalloproteinase Inhibitors.

Gerard A. Pinna, Maria M. Curzu, Gabriele Murineddu, Giorgio Chelucci, Giorgio Cignarella, Ernesto Menta, Hans W. Krell, Giulio Rastelli, Anna M. Ferrari

Journal:

Année:

2000

Fichier:

PDF, 28 KB

2000

14

ChemInform Abstract: A Series of Diarylsubstituted Oximes as Potential Substrate for New Aldose Reductase Inhibitors

Dietmar Rakowitz, Gottfried Heinisch, Peter Lukavsky, Sigrid Kiendler, Cornelia Trenkwalder, Daniela Barlocco, Giulio Rastelli, Luca Costantino

Journal:

Année:

2001

Fichier:

PDF, 29 KB

2001

15

ChemInform Abstract: Synthesis and Aldose Reductase Inhibitory Activity of a New Series of Benzo[h]cinnolinone Derivatives.

Luca Costantino, Giulio Rastelli, Giorgio Cignarella, Daniela Barlocco

Journal:

Année:

2001

Fichier:

PDF, 30 KB

2001

16

ChemInform Abstract: Synthesis and Cytotoxicity of Bis(benzo[g]indole-3-carboxamides) and Related Compounds.

Gerard A. Pinna, Maria A. Pirisi, Giuseppe E. Grella, Laura Gherardini, Jean M. Mussinu, Giuseppe Paglietti, Anna M. Ferrari, Giulio Rastelli

Journal:

Année:

2002

Fichier:

PDF, 27 KB

2002

17

ChemInform Abstract: Discovery of New Inhibitors of Aldose Reductase from Molecular Docking and Database Screening.

Giulio Rastelli, Anna Maria Ferrari, Luca Costantino, Maria Cristina Gamberini

Journal:

Année:

2002

Fichier:

PDF, 23 KB

2002

18

ChemInform Abstract: Structure-Based and in silico Design of Hsp90 Inhibitors

Miriam Sgobba, Giulio Rastelli

Journal:

Année:

2009

Fichier:

PDF, 15 KB

2009

19

In vitro Effects of Plasmodium falciparum Dihydrofolate Reductase Inhibitors on Normal and Cancer Cell Proliferation

Tiziana Rossi, Andrea Coppi, Elisa Bruni, Miriam Sgobba, Gianluca Degliesposti, Giulio Rastelli

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 285 KB

english, 2008

20

Design and Discovery of Plasmepsin II Inhibitors Using an Automated Workflow on Large-Scale Grids

Gianluca Degliesposti, Vinod Kasam, Ana Da Costa, Hee-Kyoung Kang, Nahyun Kim, Do-Won Kim, Vincent Breton, Doman Kim, Giulio Rastelli

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 626 KB

english, 2009

21

Structure-Based and in silico Design of Hsp90 Inhibitors

Miriam Sgobba, Giulio Rastelli

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 727 KB

english, 2009

22

Fragment-Based Drug Discovery: A Practical Approach. Edited by Edward R. Zartler and Michael J. Shapiro.

Giulio Rastelli

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 108 KB

english, 2009

23

A series of diarylsubstituted oximes as potential substrate for new aldose reductase inhibitors

Dietmar Rakowitz, Gottfried Heinisch, Peter Lukavsky, Sigrid Kiendler, Cornelia Trenkwalder, Daniela Barlocco, Giulio Rastelli, Luca Costantino

Journal:

Journal of Heterocyclic Chemistry

Année:

2000

Fichier:

PDF, 491 KB

2000

24

Solvent effects on the tautomerism of apigeninidin

Giulio Rastelli, Luca Costantino, Albano Albasini

Journal:

Tetrahedron Letters

Année:

1994

Langue:

english

Fichier:

PDF, 274 KB

english, 1994

25

Synthesis and biological activities of novel 17-aminogeldanamycin derivatives

Zong-Qiang Tian, Yaoquan Liu, Dan Zhang, Zhan Wang, Steven D. Dong, Christopher W. Carreras, Yiqing Zhou, Giulio Rastelli, Daniel V. Santi, David C. Myles

Journal:

Bioorganic & Medicinal Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 368 KB

english, 2004

26

Conformational analysis of phthalein derivatives acting as thymidylate synthase inhibitors by means of 1H NMR and quantum chemical calculations

Stefano Ghelli, Giulio Rastelli, Daniela Barlocco, Marcella Rinaldi, Donatella Tondi, Piergiorgio Pecorari, Maria Paola Costi

Journal:

Bioorganic & Medicinal Chemistry

Année:

1996

Langue:

english

Fichier:

PDF, 918 KB

english, 1996

27

Validation of an automated procedure for the prediction of relative free energies of binding on a set of aldose reductase inhibitors

Anna Maria Ferrari, Gianluca Degliesposti, Miriam Sgobba, Giulio Rastelli

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 278 KB

english, 2007

28

Structure-based design of 7-carbamate analogs of geldanamycin

Giulio Rastelli, Zong-Qiang Tian, Zhan Wang, David Myles, Yaoquan Liu

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2005

Langue:

english

Fichier:

PDF, 230 KB

english, 2005

29

7-Hydroxy-2-substituted-4-H-1-benzopyran-4-one derivatives as aldose reductase inhibitors: a SAR study

Luca Costantino, Antonella Del Corso, Giulio Rastelli, J.Mark Petrash, Umberto Mura

Journal:

European Journal of Medicinal Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 104 KB

english, 2001

30

Structure of Plasmodium vivax dihydrofolate reductase determined by homology modeling and molecular dynamics refinement

Giulio Rastelli, Sara Pacchioni, Marco Daniele Parenti

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2003

Langue:

english

Fichier:

PDF, 415 KB

english, 2003

31

Structure-based design of an inhibitor modeled at the substrate active site of aldose reductase

Giulio Rastelli, Paola Vianello, Daniela Barlocco, Luca Costantino, Antonella Del Corso, Umberto Mura

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1997

Langue:

english

Fichier:

PDF, 318 KB

english, 1997

32

Molecular dynamics simulations of the structure of aldose reductase complexed with the inhibitor tolrestat

Giulio Rastelli, Luca Costantino

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1998

Langue:

english

Fichier:

PDF, 444 KB

english, 1998

33

Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: structural basis of antifolate resistance

Giulio Rastelli, Worachart Sirawaraporn, Pornthep Sompornpisut, Tirayut Vilaivan, Sumalee Kamchonwongpaisan, Rachel Quarrell, Gordon Lowe, Yodhathai Thebtaranonth, Yongyuth Yuthavong

Journal:

Bioorganic & Medicinal Chemistry

Année:

2000

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2000

34

Structural bases for the inhibition of aldose reductase by phenolic compounds

Giulio Rastelli, Luciano Antolini, Stefania Benvenuti, Luca Costantino

Journal:

Bioorganic & Medicinal Chemistry

Année:

2000

Langue:

english

Fichier:

PDF, 395 KB

english, 2000

35

Binding of 1-Benzopyran-4-one Derivatives to Aldose Reductase: A Free Energy Perturbation Study

Giulio Rastelli, Luca Costantino, M.Cristina Gamberini, Antonella Del Corso, Umberto Mura, J.Mark Petrash, Anna Maria Ferrari, Sara Pacchioni

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 311 KB

english, 2002

36

ortho-Halogen naphthaleins as specific inhibitors of Lactobacillus casei thymidylate synthase. Conformational properties and biological activity

Stefano Ghelli, Marcella Rinaldi, Daniela Barlocco, Arianna Gelain, Piergiorgio Pecorari, Donatella Tondi, Giulio Rastelli, Maria Paola Costi

Journal:

Bioorganic & Medicinal Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 430 KB

english, 2003

37

A computational workflow for the design of irreversible inhibitors of protein kinases

Alberto Del Rio, Miriam Sgobba, Marco Daniele Parenti, Gianluca Degliesposti, Rosetta Forestiero, Claudia Percivalle, Pier Franco Conte, Mauro Freccero, Giulio Rastelli

Journal:

Journal of Computer-Aided Molecular Design

Année:

2010

Langue:

english

Fichier:

PDF, 965 KB

english, 2010

38

Free energy perturbation studies on binding of the inhibitor 5,6-dihydrobenzo[h]cinnolin-3(2H)one-2-acetic acid and its methoxylated analogs to aldose reductase

Giulio Rastelli, Luca Costantino, Paola Vianello, Daniela Barlocco

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 757 KB

english, 1998

39

Discovery of new inhibitors of aldose reductase from molecular docking and database screening

Giulio Rastelli, Anna Maria Ferrari, Luca Costantino, Maria Cristina Gamberini

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 483 KB

english, 2002

40

Nitrophenyl Derivatives as Aldose Reductase Inhibitors

Luca Costantino, Anna Maria Ferrari, Maria Cristina Gamberini, Giulio Rastelli

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 299 KB

english, 2002

41

Crystal Structure and Molecular Modeling of 17-DMAG in Complex with Human Hsp90

Joseph M. Jez, Julian C.-H. Chen, Giulio Rastelli, Robert M. Stroud, Daniel V. Santi

Journal:

Chemistry & Biology

Année:

2003

Langue:

english

Fichier:

PDF, 322 KB

english, 2003

42

Structural Models and Binding Site Prediction of the C-terminal Domain of Human Hsp90: A New Target for Anticancer Drugs

Miriam Sgobba, Gianluca Degliesposti, Anna Maria Ferrari, Giulio Rastelli

Journal:

Chemical Biology & Drug Design

Année:

2008

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2008

43

Binding Estimation after Refinement, a New Automated Procedure for the Refinement and Rescoring of Docked Ligands in Virtual Screening

Giulio Rastelli, Gianluca Degliesposti, Alberto Del Rio, Miriam Sgobba

Journal:

Chemical Biology & Drug Design

Année:

2009

Langue:

english

Fichier:

PDF, 142 KB

english, 2009

44

Activity Prediction and Structural Insights of Extracellular Signal-Regulated Kinase 2 Inhibitors with Molecular Dynamics Simulations

Alberto Del Rio, Benedetta Frida Baldi, Giulio Rastelli

Journal:

Chemical Biology & Drug Design

Année:

2009

Langue:

english

Fichier:

PDF, 187 KB

english, 2009

45

Assessing Protein Kinase Selectivity with Molecular Dynamics and MM-PBSA Binding Free Energy Calculations

Elena Muzzioli, Alberto Del Rio, Giulio Rastelli

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 303 KB

english, 2011

46

Synthesis, Activity, and Molecular Modeling of a New Series of Tricyclic Pyridazinones as Selective Aldose Reductase Inhibitors

Costantino, Luca, Rastelli, Giulio, Vescovini, Katia, Cignarella, Giorgio, Vianello, Paola, Del Corso, Antonella, Cappiello, Mario, Mura, Umberto, Barlocco, Daniela

Journal:

Journal of Medicinal Chemistry

Année:

1996

Langue:

english

Fichier:

PDF, 363 KB

english, 1996

47

QSAR Analysis in 2,4-Diamino-6,7-dimethoxy Quinoline Derivatives – α1-Adrenoceptor Antagonists – Using the Partial Least Squares (PLS) Method and Theoretical Molecular Descriptors

Marina Cocchi, M. Cristina Menziani, Giulio Rastelli, Pier G. de Benedetti

Journal:

Molecular Informatics

Année:

1990

Langue:

english

Fichier:

PDF, 508 KB

english, 1990

48

Conformational analysis, molecular modeling and quantitative structure-activity relationship studies of 2,4-diamino-6,7-dimethoxy-2-substituted quinazoline α1-adrenergic antagonists

Giulio Rastelli, Francesca Fanelli, M.Cristina Menziani, Marina Cocchi, Pier G. De Benedetti

Journal:

Journal of Molecular Structure: THEOCHEM

Année:

1991

Langue:

english

Fichier:

PDF, 814 KB

english, 1991

49

Advances and applications of binding affinity prediction methods in drug discovery

Marco Daniele Parenti, Giulio Rastelli

Journal:

Biotechnology Advances

Année:

2012

Langue:

english

Fichier:

PDF, 278 KB

english, 2012

50

Synthesis and aldose reductase inhibitory activity of a new series of benzo[h]cinnolinone derivatives

Luca Costantino, Giulio Rastelli, Giorgio Cignarella, Daniela Barlocco

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 133 KB

english, 2000